Research Progress on Sterilization Methods of SPF Animal Diet

doi:10. 3969 / j. issn. 1006-6179. 2025. 01. 014

Laboratory Animal Science ›› 2025, Vol. 42 ›› Issue (1): 74-79.DOI: 10. 3969 / j. issn. 1006-6179. 2025. 01. 014

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Research Progress on Sterilization Methods of SPF Animal Diet

( 1. Chongqing Academy of Animal Sciences, Chongqing 402460, China) ( 2. Farm Animal Genetic Resource Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130,China) ( 3. National Center of Technology Innovation for Pigs, Chongqing 402460,China) ( 4. Key Laboratory of Pig Industry Sciences, Ministry of Agriculture, Chongqing 402460,China)

Received:2022-06-20 Online:2025-02-28 Published:2025-03-05

SPF 动物饲料灭菌方式研究进展

( 1. 重庆市畜牧科学院,重庆 402460) ( 2. 四川农业大学畜禽遗传资源发掘与创新利用四川省重点实验室,成都 611130) ( 3. 国家生猪技术创新中心,重庆 402460) ( 4. 农业农村部养猪科学重点实验室,重庆 402460)

通讯作者: 张进威( 1993—) ,男,博士,助理研究员,研究方向为动物资源创新开发与利用,E-mail: jinweizhang50@ 163. com。
作者简介:李直( 1996—) ,男,硕士,研究方向为动物生产方面,E-mail: 1009360370@ qq. com。
基金资助:
国家自然科学基金( 32302712,32202623) ;中小规模猪场生物安全防控技术集成与示范( 24D1J01) ;重庆市技术创新与应用发展专项重点项目( cstc2021jscx-dxwtBX0007) 。

Abstract

Abstract: SPF ( Specific Pathogen Free ) animals are specific pathogen-free animals, which refer to laboratory animals that do not carry specific potential infections or conditional diseases and pathogens that greatly interfere with scientific experiments. Sterilizing the finished feed is the premise to ensure the quality of SPF animal microorganisms. Different sterilization methods have different effects on the killing effect of feed microorganisms, nutrients and animal production performance, so they must be identified and selected in the production practice process. The most commonly used sterilization method for SPF animal formula feed include irradiation sterilization and high-pressure steam sterilization. There are few reports on the use of microwave sterilization for SPF animal formula feed sterilization. This paper focuses mainly on the nutritional requirements of SPF animals, the control of microorganisms in feed, the impact of three sterilization methods on feed and animal production, and the preservation technology of SPF animal feed, and summarizes the sterilization method of SPF animal feed.

Key words: SPF animal, diet, different sterilization methods

摘要： SPF 动物即无特定病原体动物,是指不携带特定潜在感染或条件致病和对科学实验干扰大的病原实验动物。对成品饲料进行灭菌处理是保证 SPF 动物微生物质量的前提。不同灭菌方式对饲料微生物杀灭效果、营养成分及动物生产性能具有不同影响,因此在生产实践过程中须加以鉴别和选择。最常用的 SPF 动物配合饲料灭菌方式包括辐照灭菌和高压蒸汽灭菌,微波灭菌用于 SPF 动物配合饲料灭菌的相关报道较少。本文主要围绕 SPF 动物的营养需求、饲料中微生物控制、三种灭菌方式对饲料和动物生产的影响以及 SPF 动物饲料保存技术为切入点,对 SPF 动物饲料灭菌方式进行综述。

关键词: SPF 动物, 饲料, 不同灭菌处理方式

CLC Number:

Q95-3

LI Zhi , SUN Jing , LU Lu , GE Liangpeng , MA Jideng, ZHANG Jinwei. Research Progress on Sterilization Methods of SPF Animal Diet[J]. Laboratory Animal Science, 2025, 42(1): 74-79.

李直, 孙静, 陆路, 葛良鹏, 马继登, 张进威. SPF 动物饲料灭菌方式研究进展[J]. 实验动物科学, 2025, 42(1): 74-79.

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Research Progress on Sterilization Methods of SPF Animal Diet

SPF 动物饲料灭菌方式研究进展

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