Abstract: The serum electrolytes (Poasium (K), Sodium (Na), Chlorid(Cl),Calcium(Ca), Phosphate(P), total carbon dioxide (Tco2)and anion gap(AG)) from HAMS/ C Inbred mice were measured with ion-selective electrod(ISE) analyzer, and compared with KM and DBA/2 mice.The result showed that there are significant differences(P< 0.05 or P< 0.01) in P and AG of serum between female and male HAMS / C Inbred mice, but other electrolytes (Na,K, Cl and Ca) are not significant differences(P>0.05).There are significant differences(P< 0.01) in Na, K and AG of serum of HAMS / C Inbred mice, compared with KM mice, also significant differences(P< 0.01) in Na, K, Ca, P and AG of serum of HAMS / C Inbred mice, compared with DBA / 2 mice.The experiment proved that there is the special property on serum electrolytes of HAMS / C Inbred mice.

Key words: Ion-selective electrod, Electrolyte, Serum

摘要： 应用离子选择电极（ISE）型电解质分析仪，检测了HAMS／C系小鼠7项血清电解质（钠、钾、氯、钙、磷、二氧化碳总量和阴离子隙），并将所测值，在雌雄和亲代（KM和DBA／2）小鼠之间进行比较。结果表明，（1）除磷和阴离子隙雌雄间具有显著差异（P＜0.05或P＜0.01）外，其余各项指标性别间均无显著差异（P＞0.05）；（2）与KM小鼠相比，钠、钾和阴离子隙差异非常显著（P＜0.01）；（3）与DBA／2小鼠相比较，除氯外，钠、钾、钙、磷、二氧化碳总量和阴离子隙六项指标均具有显著性差异（P＜0.01）。实验证实，该品系小鼠血清电解质具有其独特的特性。

关键词: 小鼠, 血清, 电解质