Abstract: Gastritis is a common digestive tract disease. Despite the continuous improvement of living standards, its incidence has not decreased accordingly. Instead, there is a trend that the age of patients is getting younger and younger. Various animal models of gastritis have been established, including rats, mice, Mongolian gerbils, guinea pigs, and non-human primates, to further explore the pathogenesis of gastritis and better develop effective diagnostic and treatment method. Rats are the most commonly used animal models for gastritis, and this article reviewed rat models of acute and chronic gastritis.

Key words: gastritis, rat, animal models

摘要： 胃炎是一种比较普遍的消化道疾病,尽管生活水平持续提升,其发病率并没有随之降低,反而呈现出患者年 龄愈发年轻化的趋势。 现已建立了大鼠、小鼠、蒙古沙鼠、豚鼠、非人灵长类等多种胃炎动物模型,以进一步探索胃 炎的发病机制,更好地开发有效的诊疗方法。 胃炎动物模型以大鼠最为常用,本文对急性、慢性胃炎大鼠模型进行 综述。

关键词: 胃炎, 大鼠, 动物模型