laboratory animal science ›› 2019, Vol. 36 ›› Issue (02): 83-.
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Abstract: Objective To search the relevant literature of different models of facial paralysis, analyze the advantages and disadvantages of various models, and explore the production method suitable for different types of models, so as to provide experimental evidence for making animal models of facial paralysis. Method The related literatures about animal models of facial paralysis have been searched in the past decade, and various experimental animals and modeling method have been summarized. Result At present, most animals used in facial paralysis model are rats, mice and Japanese white rabbits. The method of facial nerve transection, compression and traction are the method of modeling. Conclusion There are many ways to make facial paralysis model, each has its own advantages and disadvantages. According to different research purposes, it is possible to explain the acupuncture treatment of facial paralysis.
Key words: Facial paralysis, animal modeling, modeling methods
摘要: 目的 对面瘫动物不同模型相关文献进行检索,分析各种模型制备方法的优缺点,探寻适合不同研究类型模型的制备方法,从而为面瘫动物模型的制备提供实验依据。方法 检索近十年来面瘫动物模型制备的相关文献,对各种实验动物及造模方法进行归纳总结。结果 目前面瘫模型制备使用较多的动物有大鼠、小鼠、日本大耳白兔等,造模方法有面神经切断法、压榨法、牵拉法等。结论 目前面瘫模型的制备方法较多,各有优缺点,根据研究目的不同选择不同的造模方法,才能给针灸治疗面瘫提供科学依据。
关键词: 面瘫, 造模动物, 造模方法
李小娟,赵中亭,曹朝霞,魏玉婷, 严兴科. 浅析面瘫动物模型的制备与比较[J]. 实验动物科学, 2019, 36(02): 83-.
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