Abstract: Abstract: SNP markers were developed from the transcriptome of tree shrew ( Tupaiabelangeri) abdominal adipose tissues among 6 different normal healthy tree shrews． After detecting 274 278 568 unigenes ( 43 138 415 bp) ，a total of 263 071 SNPs were identified in 262 980 unigenes ( 5. 75%) with the frequency of 1 /164bp， including transition 177 562 and transversion 85 509． A/G and C /T are the main types，accounting for 33. 85% and 33. 66% of all the SNPs， respectively． All the 262 980 SNP of all the unigenes were functionally annotated using the GenBankNrdatabas，geneontology ( GO) ，clusters of orthologous groups ( COG) and KEGG pathways． There are 1 178 SNPs annotated by GO，77 SNPs annotated by COG and 1 080 annotated by KEGG，which may link with the key genes of adipose formation and metabolism in adipose tissue，were obtained．

Key words: <p>Tree shrew, transcriptome, Single nueleotide polymorphism( SNP), functional annotation</p>

摘要： 摘要: 从正常笼养树鼩腹部的脂肪转录组数据开发SNP 分子标记。检测了6 只动物共计274 278 568 条unigene( 总长度43 138 417 bp) 序列信息后，在262 980 条unigene( 5. 75%) 中发现SNP 位点263 071 个，SNP 发生频率为1 /164 bp，其中转换( transition) 177 562 个，颠换( transversion) 85 509 个。在所有变异类型中，A/G 和C/T 发生频率最高，分别达33. 85%和33. 66%。将包含SNP 位点的262 980 条unigene 通过参比序列进行注释，并对其进行GO分类、COG 分类注释和代谢通路注释( KEGGpathway) ，结合已有研究，分别筛选到1 187 个有GO 注释、77 个有COG注释和1 080 条个有KEGG 通路注释的脂肪转录组中的可能与脂肪形成和代谢有关的SNP 标记。

关键词: <, p>, 树鼩, 转录组, 单核苷酸多态性, 功能注释<, /p>