laboratory animal science
• Article • Previous Articles Next Articles
OuyangYan TanPingping YueZuojun BaiQinghua ZhangTing Institute of Genetics,Chinese Acade my of Sciences,Beijing 1 0 0 1 0 1 ,China 〔
Received:
Revised:
Online:
Published:
欧阳燕,谭萍萍,岳作军,白琴华,张婷
Abstract: ? Thisstudyinvestigates 8lociofKMmouseinBeijing ,ShanghaiandKunmingbytechnologyofbio chemicalisoenzymeelectrophoresis.Amongthethreesubcoloniesinvestigated ,theallelicconstitutionisthesame,onlybe tweenS :KM ,K :KMandothertwosubcoloniestherearesignificantdifferencesonthealleliclociofHbbandPgm 1 .The phylogeneticdiagramshowedthatS :KMandNIHareclosetobeofoneclass,andB :KMandK :KMareclosetobeofone class.Therefore ,weregardedthatS :KM generatesdiversityingeneticcharacteristics,foritbreedsunderdifferenttechnol ogyandconditions.Thuswemuststrengthengeneticmonitoring .
Key words: KM mouse Polymorphism Genetics monitoring
摘要: 应用生物化学同工酶电泳方法 ,对京、沪和昆明市三个重点地区的昆明种小鼠在八个位点上进行群体间调查 ,在被监测的三个群体中 ,基因位点的等位基因分布基本趋于一致 ,只有上海地区的昆明种小鼠与其它两个群体在Hbb和Pgm 1位点有明显的差异 ,在聚类分析中表明北京地区的昆明种小鼠与昆明地区的昆明种小鼠种接近为一类 ,上海地区的昆明种小鼠与NIH小鼠接近为一类 ,因此 ,我们认为上海地区被调查单位的昆明种小鼠 ,可能是由于长期饲养在不同的技术和条件下 ,在遗传特性方面发生了变化 ,应加强遗传监控
关键词: 昆明种小鼠, 多态型, 遗传监控
OuyangYan TanPingping YueZuojun BaiQinghua ZhangTing Institute of Genetics,Chinese Acade my of Sciences,Beijing 1 0 0 1 0 1 ,China 〔. Study on Variants of KMMouse Subcolonies in Beijing ,Shanghai and Kunming[J]. laboratory animal science.
欧阳燕,谭萍萍,岳作军,白琴华,张婷. 京、沪和昆明地区昆明系小鼠群体间的差异研究[J]. 实验动物科学.
0 / / Recommend
Add to citation manager EndNote|Ris|BibTeX
URL: http://www.sydwkx.com/EN/
http://www.sydwkx.com/EN/Y1999/V16/I04/29