关键词: <, p>, 椎间盘, 纤维环缝合, 修复时间, 实验研究 <, /p>

Abstract: Abstract: Objective Preform the animal experimental study to research the characteristics of intervertebral disc biomechanical strength in different periods after the annulus fibrosus suture． Method A total of 40 sheep were underwent retroperitoneal 3 levels exposure of the lumbar spine． The Control Group did not penetrate into the annulus fibrosus． The Ｒesearch Group penetrated into the annulus fibrosus and perform annulus fibrosus suture． In Ｒesearch Group，at 3 months after surgery，Group A were taken MＲI images and underwent biomechanical testing to assess the strength of the disc． Histology was also conducted． Group B were performed 6 months after surgery． Group C were performed 12 months after surgery． Ｒesult The biomechanical strength of the disc at 3 months after operation was( 1. 39 ± 0. 68) MPa，( 2. 04 ± 0. 88) MPa at 6 months． ( 3. 58 ± 1. 10) MPa at 12 months，and it was close to the Control Group with( 3. 90 ± 1. 59) MPa． In Ｒesearch Group，loss of intervertebral height was( 1. 01 ± 0. 29) mm after 3 months． ( 1. 90 ± 0. 65) mm after 6 months，( 2. 04 ± 0. 85) mm after 12 months． Conclusion Annulus fibrosus suture play an important role in the maintenance of the mechanical strength of the intervertebral disc，also promote the repair of annulus fibrosus． And the biomechanical strength of the intervertebral disc was correlated with the repair time of annulus fibrosus．

Key words: <p>disc, annulus fibrosus suture, repair process, experimental study</p>