关键词: 黑蒜, 链脲佐菌素, 血糖

Abstract: Abstract: Objective To investigate the effect and mechanism of the “black garlic”( Black garlic) on the body weight and the blood glucose in diabetic rats induced by streptozotocin． Method The diabetic rat model was established by intraperitoneal injection of 50mg / kg streptozotocin． Black garlic was administrated to the rats by oral gavage for 30 days． Body weight and blood glucose level before and after 30 － day oral gavage were determined respectively． Ｒesult Black garlic at the dose of 10g / kg has no effect on body weight and blood glucose level of the control rats． At the high ( 10 g / kg) and the middle ( 5 g / kg) doses，body weight of the black garlic treated group declined，while the blood glucose level increased continuously compared with the untreated group． But there were no significant differences between the two groups． At the low dose ( 2. 5g / kg) ，weight loss of the treated group was relieved and the blood glucose increased slowly compared with those of the untreated group． And the differences were statistical significant． Conclusion This study indicates that proper consumption of black garlic reduces blood glucose level，and delays the development of diabetes． Further studies are expected to explicate the mechanism of the black garlic．

Key words: Black garlic, streptozotocin, blood glucose