关键词: 耐力运动, 氧化应激, 心肌组织, SD 大鼠

Abstract: Abstract:Objective To analyze the effects of different types of endurance training on oxidative stress of myocardial tissue in Sprague-Dawley rats，and thereby to provide rational movement scheme to improve the myocardial antioxidant capacity． Method A total of 48 male SD rats (6 weeks) were enrolled in the study． The study consisted of control group (n = 12)，low intensity exercise group (n = 12)，moderate intensity exercise group (n = 12) and highly intensity exercise group ( n = 12)． The endurance exercise training groups exercised for 6 weeks and the control group maintained their daily eating habits． superoxide dismutase (SOD) activity，glutathione peroxidase (GSH － Px) activity，malondialdehyde (MDA) content were measured after the 6 weeks experiment． Result After 6 weeks endurance exercise training intervention，compared with control group，the SOD activity were higher in moderate intensity exercise group (P ＜ 0． 01)，and significantly higher in highly intensity exercise group (P ＜ 0． 01);the GSH － Px activity were higher in low and moderate intensity exercise group (P ＜ 0． 05 or P ＜ 0． 01)，and significantly higher in highly intensity exercise group (P ＜ 0． 01)． Moreover，the levels of MDA significantly enhanced in highly intensity exercise group (P ＜ 0． 01)． Conclusion The low and moderate intensity exercise group were effective in improve the myocardial antioxidant capacity of rats，particularly in moderate intensity exercise group．

Key words: endurance exercise training, oxidative stress, myocardial tissue, SD rats