关键词: 实验动物, 小鼠, 豚鼠, 寄生虫, 病毒

Abstract: Abstract:Objective To screen the infection of parasites and viruses，including Sendai virus ( SeV)、Mouse hepatitis virus (MHV)、Lymphocytic choriomeningitis virus ( LCMV)，in 90 laboratory mice and 45 laboratory guinea pigs of Kunming area． Method The specimen of 90 mice and 45 guinea pigs were selected from 3 different company randomlies． According to the description of experimental monitor methods of national standard and the protocol of virus assay kit ，parasites and viruses (SeV and MHV of mice ，LCMV and SeV of guinea pigs) of 90 laboratory mice and 45 laboratory guinea pigs were investigated． Result Ectoparasite was detected from 3 animals in 90 mice，detection rate is 3. 3% ． Endoparasite was detected from 20 animals in 90 mice，detection rate is 22. 2% ． Ectoparasite was detected from 4 animals in 45 guinea pigs，detection rate is 8. 9% ． Endoparasite was detected from 9 animals in 45 guinea pigs ，detection rate is 20. 0% ，SeV of mouse and MHV were not detected， LCMV of guinea pigs and SeV of guinea pigs were not detected． Conclusion The situation of virus infection control is quite good，but both ectoparasite and endoparasite infection is relatively common in Kunming area． The works of quality control of laboratory animals should be improved in Kunming area． The quality monitoring of laboratory animals is very important in the biomedical research．

Key words: experimental animals, mice, guinea pigs, parasites, virus