Abstract: Abstract: Inflammatory bowel disease ( IBD) is a chronic and non-specific inflammatory disease which comprises Crohn's disease( CD) and ulcerative colitis( UC) ． The typical clinical manifestations are abdominal pain，diarrhea and bloody mucopurulent stool． The disease is caused by the interaction of a number of factors，generally including infected，genetic，environmental， immunologic abnormalities and other factors． The experimental models of IBD have been proven to be important tools to investigate the potential therapeutic agents． This review is intended to cover recent advances in suitable animal models and describe its features of IBD animal models．

Key words: <p>inflammatory bowel disease, animal models, research progress</p>

摘要： 摘要: 炎症性肠病是一组病因不明的慢性肠道疾病，包含克罗恩病和溃疡性结肠炎，以腹痛、腹泻、便血等为主要病理特点。目前认为本病由多因素相互作用所致，主要包括感染、免疫、遗传、环境和精神等因素。炎症性肠病实验动物模型的发展为新药的研究和开发创造了条件，本文旨在对炎症性肠病的常用造模方法及理想动物模型的特点进行综述。

关键词: <, p>, 炎症性肠病, 动物模型, 研究进展<, /p>