Abstract: Abstract: Objective To study the anesthesia effect of Ketamine and Sumianxin Ⅱ on minipigs，to investigate the effects of two kinds of anesthetic on physiology of animal． Method Ketamine and Sumianxin Ⅱ were mixed together，the volume ( between 0． 3 to 0． 5 mL /kg) of the mixture was used for anesthesia，then the anesthetic effect and physiology index were recorded． Ｒesult With the increasing of anesthesia dose，the length of anesthesia effect － act，muscle relaxant and eyelid reflex disappearing were decreasing． The heart rate and respiratory rate of animals in high dose ( 0. 4—0. 5 mL /kg) group higher than low dose ( 0. 3—0. 4 mL /kg) group． The mean arterial pressure and the oxygen saturation were similar between two groups． Conclusion 0. 3—0. 4 mL /kg could be used safely for anesthesia on minipig ，this dose could offered not only good anesthesia effect but also little impact on physiology indexes．

Key words: <p>Bama minipig, Ketamine, Sumianxin Ⅱ, anesthesia</p>

摘要： 摘要: 目的研究氯胺酮和速眠新Ⅱ复合麻醉方法用于巴马小型猪实验的麻醉效果，初步观察复合麻药对动物机能指标的影响。方法使用氯胺酮和速眠新Ⅱ按2∶ 1. 5( mL) 的体积制成混合麻醉剂，在0. 3—0. 5 mL/kg 的剂量范围内，给予动物一定剂量的麻药进行麻醉，记录麻药剂量、麻醉效果和生理指标。结果随着麻醉剂量的增加，麻药起效时间、肌松时间和眼睑反射消失时间均降低; 动物心率和呼吸频率增加，对血压影响不大。结论0. 3—0. 4 mL/kg 可以作为安全剂量用于小型猪的麻醉，不但起到良好的麻醉效果，对生理指标影响也不大。

关键词: <, p>, 巴马小型猪, 氯胺酮, 速眠新Ⅱ, 麻醉<, /p>