laboratory animal science ›› 2011, Vol. 28 ›› Issue (03): 47-50.

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Electrocardiogram of Healthy Rhesus Monkeys

  

  • Online:2011-06-30 Published:2013-06-04

健康恒河猴心电图研究

  

  1. (1.中国食品药品检定研究院国家药物安全评价监测中心,北京100176)
    (2.首都医科大学附属北京天坛医院心内科。北京100050)

Abstract: Objective To investigate the electrocardiogram(ECG)features of rhesus monkeys in consciousness. Methods Sixty healthy rhesus monkeys,2—3 years old,2~3.5 kg,and 30 each gender,were selected.ECG changes of the lead I,2,3,aVR,aVL,aVF in resting conscious monkeys were examined,and the average heaM rate,mean electrical axis,P wave,QRS complex,amplitude of T wave,PR interval,QT interval and so on,were calculated.Results and Conclusions Sinus rhythm was found in all the 60 rhesu8 monkeys.In most of the rhesus monkeys,the P wave was upright in H lead,S wave was absent in 2、3、aVF  leads,and there was no Q wave in aVR lead.The average voltage of R wave in female rhesus monkeys was significantly higher than that of the males (P<0.005).In rhesus monkeys,the P wave is sharp,the QRS is diversified,the QT interval K value is 0.298± 0.030,the ST segment locates at the isoelectric line,and the T wave is smooth in six leads and upright in the II lead.In conclusion,we established the basic ECG data of rhesus monkeys.

Key words: Rhesus monkeys, Electrocardiogram(ECG)

摘要: 目的研究健康恒河猴在清醒状态下的心电图特点。方法选择60只2—3岁健康恒河猴,体重2—3.5kg; 雌雄各30只;在环境安静、动物清醒状态下,测定I、Ⅱ、Ⅲ、aVR、aVL、aVF六个导联的心电图变化,并计算平均心 率,平均心电轴,P波、QRs波群和T波的振幅,PR间期、QT问期等指标。结果60只恒河猴均为窭性心律,并发 现在肢体Ⅱ导联中,P波均为向上直立波,Ⅱ、Ⅲ、aVF导联中大部分恒河猴没有s波,aVR导联中大部分恒河猴没 有Q波。雌性恒河猴R波电压平均值明显高于雄性恒河猴平均值(P<0.005)。恒河猴P波较尖,QRs波群多样 化,QT问期的K值范围是0.298 4-0.030,ST段位于等电位线,T波以圆滑为主,Ⅱ导联中绝大部分为直立。结论 此研究建立了恒河猴心电图相关基础数据,为相关的研究提供了参考。

关键词: 恒河猴, 心电图

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