Abstract: Objective To compare the performance of closed exhaust ventilation central cages ( EVC ) and individual ventilated cage ( IVC) systems for rats and mice. Method Through the breeding space of the EVC system and ICV system, the operation process ( cage changing process and cleaning process) , damage rate, overall disinfection and cleaning process, mouse breeding environmental conditions ( number of air changes and wind speed and ammonia concentration ) , cage evaluation of indicators such as internal noise decibels, power outages or mechanical failures, and alarm systems. Result EVC cage covers a smaller area and easier to wipe and clean. The operation of observation, cage replacement and cleaning process are more simple than IVC system, escapically with lower accessory loss and energy consumption. But IVC cage performs better in washing, sound insulation,etc.

Key words: closed breeding, exhaust ventilation central cage system, individual ventilated cage system, laboratory animals

摘要： 目的 探讨两种密闭式笼具系统:中央排风通气笼具( EVC)和独立通气笼具( IVC)的性能比较。 方法 通过对 EVC 和 IVC 的占地面积、使用操作流程(换笼流程及清洗流程) 、损坏率、整体消毒清洁流程、小鼠饲养环境条件(换气次数、风速及氨浓度) 、笼盒内噪音、断电或机械故障的报警系统等指标进行对比评价。 结论 EVC 笼架占地面积小、节省空间及更容易清洗,观察、换笼操作相对简单,配件损耗低且能耗更低,但 IVC 清洗及隔音效果表现更佳。 结论 EVC 是一种节省空间、节能、环保且绿色的优化方案。

关键词: 屏障设施, 中央排风通气笼具系统, 独立通气笼具系统, 小鼠