Abstract: Abstract: Objective To analysis the blood biochemical parameters influenced by age and gender of inbreed Wuzhishan miniature pigs． Method 34 6-month-old pigs ( 7 ♂，27 ♀) ，as well as 21 pigs of 5—6 years old( 8 ♂，13♀) from F17，F18 offsprings of inbred WZSP were selected． After 12 hours of fasting，blood was collected via the superior vena cava and biochemical indexes were analyzed by full-Automatic biochemical analyzer． Ｒesult In all the blood biochemical indexes，3 of them showed gender differences ( P ＜ 0. 05) between young pigs，while 7 of them showed gender differences ( P ＜ 0. 05) among aged pigs． Meanwhile 16 of the blood biochemical indexes showed age differences ( P ＜ 0. 05) ． Conclusion The blood biochemical indexes of WZSP inbred lines display a significant age difference ( P ＜ 0. 05) ． This provides a basic reference data for choosing the aged miniature pigs as human aging animal models．  

Key words: Wuzhishan miniature pig, biochemical index, senior pig

摘要： 摘要: 目的了解猪龄和性别对五指山小型猪( WZSP) 近交系血液生化指标的影响。方法WZSP 近交系F17、F18 6 月龄青年猪34 头( 7♂，27♀) ，5—6 高龄猪21 头( 8♂，13♀) ，禁食12 h 后经由前腔静脉采血，用全自动生化分析 仪检测血液生化指标。结果青年猪和高龄猪有部分血液生化指标具有性别差异( P ＜ 0. 05) ，其中青年猪有3 项 高龄猪有7 项; 青年猪和高龄猪有16 项血清生化指标具有差异( P ＜ 0. 05) 。结论WZSP 近交系血液生化指标有 着明显的年龄差异，这对选用高龄猪作为人类老年化动物模型提供了基础参考数据。

关键词: 五指山小型猪, 生化指标, 高龄猪