Abstract: Abstract: Objective To copy the animal model of myocardial anoxia and myocardial ischemia，observe the protect effect of Guanmaikang collocystis on animal model of myocardial anoxia and myocardial ischemia． Methods The rats ranine vein were injected through hypophysin to induce the model of acute ischemic myocardium，and the change of ECG T-wave of all the groups injected Pituitrin ( Pit) were observed at different intervals． Closed container induced oxygen deficient circumstances in normal atmosphere，the ability of Guanmaikang collocystis on mouse to endure pneumatorexis was observed． Results Guanmaikang collocystis can antagonize the change of Twave by Pit，a nd lengthened the survival time of mouse in Pituitrin． Conclusion Guanmaikang collocystis have the effect of anti-myocardial ischemia and the ability of enduring oxygen deficient circumstances in normal atmosphere． kuanmaikang collocystis; myocardial ischemia;

Key words: kuanmaikang collocystis, myocardial ischemia, pneumatorexis in normal atmospher

摘要： 摘要: 目的复制心肌缺血缺氧动物模型，观察冠脉康胶囊抗心肌缺血缺氧作用。方法采用大鼠舌下静脉注射 垂体后叶素诱发急性心肌缺血模型，观察各组注射垂体后叶素后不同时间段内心电图T 波高度变化; 应用密闭容 器造常压缺氧环境，观察冠脉康胶囊对小鼠耐缺氧能力。结果冠脉康胶囊能对抗垂体后叶素引起的T 波变化; 能延长常压缺氧条件下的小鼠存活时间。结论冠脉康胶囊具有抗心肌缺血作用，并具有耐常压缺氧能力。

关键词: 冠脉康胶囊, 垂体后叶素, 常压缺氧, 心肌缺血