laboratory animal science

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Evaluation of Sterilization Effect of Pulsant Vacuum Sterilizer

ZHANG Xi-mu~1,TIAN Yong-lu~1,ZHU De-sheng~   

  1. (1),HE Zheng-ming~2,LI Gen-ping~3,MENG Xan-li~4,WANG Kui-bo~4(1.Laboratory Animal Centre,Peking University,Beijing 100871,China) (2.National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100176,China)(3.Beijing Administrative Office of Laboratory Animal,Beijing 100101,China)(4.SHINVA Medical Instrument Co.LTD,Zibo 255086,China
  • Received:2009-12-28 Revised:2009-12-28 Online:2009-12-28 Published:2009-12-28

脉动真空灭菌器灭菌效果的评定

张希牧;田永路;朱德生;贺争鸣;李根平;孟宪礼;王魁波;   

  1. 北京大学实验动物中心;中国药品生物制品检定所;北京市实验动物管理办公室;山东新华医药器械股份有限公司;

Abstract: The sterilization effects for feeds,bedding materials,drinking water and cages in the same package under the same sterilizing condition and for the single article under different sterilizing conditions with pulsant vacuum sterilizer were evaluated by Bacillus Stearothermophilus as indicator.This not only verified the killing effect of pulsant vacuum sterilizer under commonly sterilizing condition,but also optimized the sterilization parameter of pulsant vacuum sterilizer.

Key words: Pulsant vacuum sterilizer, Sterilization effect, Sterilization parameter

摘要: 采用嗜热脂肪杆菌芽胞菌片作为指示菌,通过其在同一灭菌条件下对同种包装方式的饲料、垫料、动物饮用水以及笼具等多种物品的灭菌效果以及不同灭菌条件下对单一物品的灭菌效果进行分析评定,进而验证脉动真空灭菌器在常用的灭菌条件下的灭菌效果,同时对该灭菌器的灭菌参数进行了优化。

关键词: 脉动真空灭菌器, 灭菌效果, 灭菌参数