Abstract: Objective To discuss the anesthetic effect and its influencing factors of pentobarbitol sodium on dogs.Methods 540 dogs were anesthetized by 2.5%and 3% pentobarbital sodium intravenously in different week,the anesthetic effect and the acting time were recorded.Results Anesthetic effect were divided into good,moderate,bad,and death according to the reaction of dogs,which occurred in 418(77.4%),55(10>2%),47(8.7%),and 20(3.7%) respectively.Acting duration was less than 30 mins in 91.5% of dogs.Conclusion Anesthetic effect in laboratory dogs by using 2.5% pentobarbital sodium intravenously was safe and effective,and is more suitable when applying in large amount of dogs,Overdose of anesthesia could be reduced through standardize administration.

Key words: Dog, Pentobarbitol sodium, Anesthesia

摘要： 目的总结戊巴比妥钠静脉注射家犬全麻的效果及影响因素。方法对540只家犬在不同周次分别进行3%和2.5%戊巴比妥钠静脉注射麻醉,对麻醉效果及所需时间进行总结。结果麻醉效果优418只(77.4%),良55只(10.2%),差47只(8.7%),麻醉过程中死亡20只(3.7%)。91.5%犬只可以在30 min内完成麻醉。结论通过规范化管理,静脉注射2.5%戊巴比妥钠进行实验动物犬麻醉安全、省时,完全可以满足动物外科教学实验动物犬的麻醉,通过适当降低药物浓度及掌握合适的注药速度可明显减少麻醉过量的发生。

关键词: 犬, 戊巴比妥钠, 麻醉