laboratory animal science

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Anaesthesia Effect of Intramuscular Injection of Sodium Pentobarbital and Diazepam Combined with Intravenous Sodium Pentobarbital on Pignets

ZHANG Dong,YU Pei-hua,LIU Tian-yun   

  1. (Peking Union Medical College Hospital,Beijing 100730,China
  • Received:2008-08-28 Revised:2008-08-28 Online:2008-08-28 Published:2008-08-28

一种麻醉方法对实验小型猪的效果观察

张栋;郁佩华;刘天云;   

  1. 中国医学科学院中国协和医科大学北京协和医院;

Abstract: Objective To investigate the anaesthesia effect of intramuscular injection of sodium pentobarbital and diazepam combined with intravenous sodium pentobarbital on pignets.Methods Sixteen pignets were initially anesthetized by intramuscular injection of sodium pentobarbital and diazepam.The general anesthesia was maintained by an intravenous dose of sodium pentobarbital.Result Complete anesthesia was observed in all of the 16 pignets.The procedure resulted in complete relaxation of the pignet muscle,allowing experimental manipulation in vivo.All the anesthetized pignets survived after the operation.Conclusion Intramuscular injection of sodium pentobarbital and diazepam combined with intravenous sodium pentobarbital has a good anaesthesia effect in pignets.The procedure provides a useful tool for in vivo studies that demand a complete state of anesthesia.

Key words: Pignets, Anaesthesia

摘要: 目的探讨戊巴比妥钠和地西泮肌肉注射与戊巴比妥钠静脉麻醉对实验小型猪的麻醉效果。方法对16头实验小型猪进行戊巴比妥钠诱导麻醉加地西泮肌肉注射配合戊巴比妥钠静脉滴注麻醉控制效果进行观察并分析。结果成功麻醉16例,占100%。结论采用戊巴比妥钠肌肉注射诱导麻醉配合静脉滴注麻醉效果好,麻醉过程平稳,肌肉松弛效果显著,生命体征稳定,手术后苏醒快。

关键词: 实验小型猪, 麻醉