Abstract: Objective To know the real situation of Shigella infection and the sensitivity to antibiotics among rhesus monkeys of sale-waiting colony and recently introduced colony in a monkeys feeding farm.Methods The monkey feces were cultured,the bacteria were isolated and identified,and the antibiotic sensitive tests were carried out in the light of the method for Shigella strains.Results The main infective strain of Shigella was B-substrain in the two colonies.In the sale-waiting colony,the rate of D-substrain infection was also higher,however,D-substrain infection was not found in the recently introduced colony.The rate of C-substrain infection was higher in the recently introduced colony.In the sale-waiting colony,the sensitivities of the bacteria to cefotaxime and cefazolin were higher;however,most of the strains were showed to be drug-resistant.In the recently introduced colony,the sensitivities of the bacteria to ceftriazone,cefotaxime,furazolidone,and cefoperazone were higher and the sensitive rate in the recently introduced colony was higher than in the sale-waiting colony.Conclusion The results are able to come up with useful information for breeding of rhesus monkeys,and prevention and treatment of shigellosis.

Key words: Rhesus monkey, Shigella, Antibiotic sensitivity

摘要： 目的对原有猴群及新引入猴群进行志贺菌带菌情况及抗生素敏感性调查。方法采用国标(GB/T14926.47-2001)的检测方法,对1 149份猕猴粪便样品进行细菌分离、鉴定及药敏实验。结果原猴群感染率比引入猴群高2.75%,且两组均以B群志贺菌感染为主;原猴群D群感染率也较高,而新引入猴群无D群感染,C群感染率较高。药物敏感性试验,原猴群感染菌对头孢噻肟、头孢唑啉较敏感,但高敏菌株并不多,绝大多数菌株耐药;新引入猴群感染菌对头孢曲松、头孢噻肟、痢特灵、头孢哌酮较为敏感,且高敏感率较原猴群高。结论由于引入新的猴群,志贺菌的分型较复杂,且综合药物敏感性较差。此试验为动物生产及防病治病提供了依据。

关键词: 猕猴, 志贺菌, 药物敏感性