laboratory animal science

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Statistical Analysis of Normal Body Temperature of Rabbits in Pyrogen Test

DU Ying, XU Wen\|yu, REN Jun,\ HUANG Qing\|quan, HE Zheng\|ming, LI Guan\|min   

  1. (National Institute for the Control of Pharmaceutical and Biological Products, Beijing\ 100050
  • Received:2003-03-25 Revised:2003-03-25 Online:2003-03-25 Published:2003-03-25

热原检查用家兔正常体温的统计分析

杜颖,徐文瑜,任珺,黄清泉,贺争鸣,李冠民   

  1. 中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所 北京100050 ,北京100050 ,北京100050 ,北京100050 ,北京100050 ,北京100050

Abstract: Objective\ To analyse the kinetic change of normal body temperature of rabbits in pyrogen test. Methods\ To measure the normal body temperature of rabbits according to the rules on pyrogen test, and to analyse these data using biological statistics. Results\ These data show statistical significance between the normal body temperature of rabbits in 5\_7 morth and 2\_4 morth in one year(\%P\%<0\^05), and statistical significance between the average value of normal temperatuce of the second used rabbits and that of the first used rabbits, the temperature difference is 0\^07℃(\%P\%<0\^05). Conclusion\ The normal body temperature of rabbits in pyrogen test changes with season and times to be used.

Key words: Pyrogen test, Rabbit, Normal body temperature, Statistical analysis

摘要: 目的 分析热原检查用家兔正常体温的动态变化。方法 按照有关规程对热原检查用家兔进行体温测定 ,并采用生物统计方法进行统计分析。结果 热原检查用家兔一年中正常体温 5— 7月份与 2— 4月份存在显著性差异 (P <0 0 5 ) ;二次用兔的正常体温平均值明显高于新兔的正常体温平均值 ,二者温差为 0 0 7℃ ,且存在显著性差异 (P <0 0 5 )。结论 热原检查用家兔正常体温随时间和使用状态而有所变化

关键词: 热原检查, 家兔, 正常体温, 统计分析