laboratory animal science

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Study on Treatment Hepatocystis Disease in Rhesus monkeys with Antiperiodics

WU Jun 1\ HU Li-ya 2 SAI Bai 2   

  1. (1.Institute of Antiparasitic Diseases of Guangdong province, Guangzhou\ 510300) (2.National Laboratory Primate Center of China, Yunnan, Jinghong\ 666100
  • Received:2001-12-25 Revised:2001-12-25 Online:2001-12-25 Published:2001-12-25

抗疟药治疗恒河猴肝囊原虫血症的初步研究

吴军,胡黎娅,赛白   

  1. 广东省寄生虫病防治研究所,中国实验动物云南灵长类中心,中国实验动物云南灵长类中心 广州510300 ,景洪666100 ,景洪666100

Abstract: Antiperiodics was weed to treatment the Hepatocystis of monkeys and the other available drugs were evaluated for Hepatocystis treatment. The results showed that the artenether and quinine can inhibit the gamonic of Hepatocystis in monkeys' blood. Monkeys were not observed to have the side reaction after taking those medicines.

Key words: Rhesus monkey, Hepatocystis, Antiperiodics, Treatment

摘要: 应用多种抗疟药物治疗恒河猴肝囊原虫血症 ,初步筛选出对肝囊原虫血症有疗效的药物。实验结果表明 ,蒿甲醚和奎宁对猴外周血液中的肝囊原虫配子体有一定的抑制和杀灭作用 ,能暂时缓解或消除猴的原虫血症。通过对猴在服药前后的血液生化指标变化的测试表明 ,实验所用药物对猴没有产生不良影响。

关键词: 恒河猴, 叶猴肝囊原虫, 抗疟药