Abstract: Some puppy in one feedlot were dead with respiratory symptom. A germ was isolated from many visceras of the puppy and identified as strain E.coli. According to clinical symptom, pathological change and the results of the bacterial isolation and characterization, it can be affirmed that the canine death was resulted from E.coli's infection in lungs.

Key words: E.coli's

摘要： 北京某饲养场的幼犬成窝死亡 ,以呼吸道症状为主 ,从多处脏器分离出致病菌一株 ,根据细菌鉴定结果 ,结合临床表现和病理观察 ,证实送检犬因埃希氏大肠杆菌移位引起大叶性肺炎是导致死亡的主要原因 ,同时伴有肠道反应。药敏结果可见 ,本菌对大部分抗生素产生耐药 ,说明滥用抗生素引起机体功能紊乱 ,抵抗力下降 ,致使正常菌群移位 ,是导致感染的主要原因。通过动物试验 ,腹腔注射此株埃希氏大肠杆菌 ,可导致小鼠菌血症、败血症而死亡 ,而持续一周食入本菌 ,不但不致病 ,且能增强体质 ,可考虑用作饲喂微生态制剂。

关键词: 埃希氏大肠杆菌, 犬