实验动物科学 ›› 2014, Vol. 31 ›› Issue (01): 57-60.

• 研究简报 • 上一篇    下一篇

一例老年恒河猴消化系统疾病诊断

  

  1. (首都医科大学基础医学院实验动物学系,北京100069)
  • 出版日期:2014-02-28 发布日期:2014-05-14
  • 基金资助:

    北京市教委科技计划项目(No. 3500 - 11320040)

Diagnosis of Digestive System Disease on an Old Macaca Mulatta

  • Online:2014-02-28 Published:2014-05-14

摘要: 摘要:本实验室人工饲养的一只老年恒河猴出现以腹泻、排脓样便、消瘦为主要体症的急性疾病。为研究老年恒河 猴消化器官病变的发生情况并进行诊断,本实验采用临床体征结合常规HE 染色对其消化系统进行组织学观察,结 果发现恒河猴的消化系统组织存在不同程度的病变,包括各种炎性细胞浸润,杯状细胞减少及黏液分泌减少,消化 道黏膜的变性、坏死,消化腺的萎缩等,诊断该老龄猴为生理性衰老。

关键词: 老年恒河猴, 病理诊断, 消化系统

Abstract: Abstract:An old rhesus monkey developed diarrhea,marasmus as the main syndrome of acute disease. To study the pathological changes of digestive system in old rhesus monkey,stomach and duodenum was investigated by general observation and routine HE staining. It was found that varying degrees of pathological changes were appeared in digestive system of rhesus monkeys including a variety of inflammatory cell infiltration,goblet cells and mucus secretion reducing,degeneration or necrosis of the digestive gut mucosa,digestive gland atrophy. It was showed that this older monkeys was physiological senility.

Key words: old rhesus monkey, pathological diagnosis, digestive system

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