关键词: Wistar 大鼠, 生存, 致癌性, 体质量, 进食量

Abstract: Abstract:In order to measure survival，body weight and food intake of Wistar rats feeding for two years，tumor occurrence and survival of Wistar rats were observed for two years，and food intake and body weight were investigated weekly． The results showed mortality and survival time of male rats were higher than female rats， spontaneous tumor incidence of female rats were slightly higher than male rats，and multi-organ tumors were found in one animal． Compared with female rats，food intake and water intake of male rats had no apparent change trends． Body weight grew obviously in earlier and obtained peak later，and then declined slightly． Daily food consumption and body weight percentage declined earlier in the test，and slightly rebounded after the minimum value was reached． Normal reference range of Wistar rats feeding for two years was set up in order to evaluate

Key words: Wistar rats, survival, carcinogenicity, body weight, food intake