关键词: BALB / c 小鼠, 受孕, 检测方法

Abstract: Abstract:Objective To compare and study three inspecting methods which test whether the mice were pregnant or not． Method Check and study the fertilization of the same mice group with three methods． The first method was to use vaginal suppository to identify the mice were pregnant or not; the second method was to use vaginal suppository and check mice’s weight; the third method was to check mice’s weight． Ｒesult The first method sees the sensitivity of the mice’s pregnancy was 0. 71 and the specificity was 0. 47． According to the second method，the sensitivity was 0. 71 and the specificity was 0. 96． And third method shows that the sensitivity was 0. 96 and the specificity was 0. 94． Conclusion For the methods detecting mouse gestation GD 10 and late state，observing change of weight is more reliable and practical than other methods in the process of inspecting pregnant mouse in the GD 10 period and late stage．

Key words: BALB / c mice, pregnancy, inspecting method