Abstract:Although great progress has been made in the ethical review of laboratory animal welfare in China, there are still some problems in the performance of IACUC including the unclear legal status of IACUC, the absence of rules and regulations, weak ability of IACUC and the insufficient attention of researchers. Based on the ethical review method of biomedical research involving human beings, 4 suggestions are put forward. Firstly, the management requirements of the ethical work of laboratory animal welfare are put forward in the “ Statute on the Administration of Laboratory Animal Use” . Secondly, it formulates the national level of laboratory animal welfare ethics review regulation. Thirdly, the ability of IACUC should be improved by training. Finally, the project application and paper publishing process should strictly abide by the animal welfare ethics. It is urgent for China to establish welfare ethical review system, to improve the ethical review of laboratory animal welfare and facilitate the development of science and technology.