实验动物科学 ›› 2021, Vol. 38 ›› Issue (4): 78-.

• 研究进展 • 上一篇    

慢性支气管炎动物模型的研究进展

  

  1. 北京中医药大学中药学院,北京 102488
  • 出版日期:2021-08-28 发布日期:2021-10-29

Advances in Animal Models of Chronic Bronchitis

  1. School of Chinese Material Medica, Beijing University of Chinese Medicine, Beijing 102488, China
  • Online:2021-08-28 Published:2021-10-29

摘要:

摘要:探讨慢性支气管炎( chronic bronchitis,CB)动物模型的实验研究进展和发病机制。 CB 的影响因素复杂多变,与感染或非感染因素长期刺激相关。 其发病不仅与有害气体、粉尘、细菌及病毒相关,还与年龄、气候、机体免疫等因素有关。 本文总结了烟熏法、化学药物法及复合刺激法的 CB 动物模型的构建方法,旨在为相关实验提供选择和制作 CB 动物模型提供参考和理论支持。

关键词: ">慢性支气管炎丨动物模型丨制备方法

Abstract:

Abstract:To study the chronic bronchitis animal model of experimental research progress and pathogenesis. The influencing factors of chronic bronchitis are complex and changeable, which are related to long-term stimulation of infectious or non-infectious factors. Its pathogenesis is not only related to harmful gases and dust, bacteria, viruses, but also related to age, climate, organism immunity and other factors. This paper summarizes the method of building animal models of chronic bronchitis, such as fumigation, chemical drug and compound stimulation, in order to provide research progress and theoretical support for other scientists in animal models of chronic bronchitis.

Key words: ">chronic bronchitis丨 animal models丨preparation methods