Abstract:

Abstract:Cough variant asthma ( CVA) is a special type of asthma, one of the main causes of chronic cough. At present, many scholars believe that CVA is a precursor disease of typical asthma or a transitional manifestation of typical asthma when airway inflammation is relatively mild. There is 30% of CVA may evolve into typical asthma. Therefore, early detection and early treatment of CVA are particularly important. At present, the pathogenesis of CVA is not clear. In-depth research has become a more important direction. There are many animal experiments based on CVA models, but the method are not the same. This article focuses on cough variation. The pathological changes of asthma and the different modeling method in the past ten years are summarized.