实验动物科学 ›› 2018, Vol. 35 ›› Issue (06): 81-.

• 研究进展 • 上一篇    

弱视动物模型的制作与评价

  

  1. (1. 甘肃中医药大学针灸推拿学院,兰州 730000)(2. 达州市中西医结合医院,达州 635000)
  • 出版日期:2018-12-28 发布日期:2020-08-31

Preparation and Evaluation of Amblyopia Animal Model

  • Online:2018-12-28 Published:2020-08-31

摘要: 弱视是儿科常见的一种眼科疾病,为儿童的生活带来了极大的困扰,建立理想的弱视动物模型对于该病症的实验研究尤为重要。目前弱视动物的造模方法主要有:眼睑缝合法、眼直肌切断法、黑暗环境饲养法、视网膜摘除法。本文综述并分析了不同动物种类弱视模型制作方法的优、缺点,为科研实践中选择使用弱视模型提供依据。

关键词: 弱视, 动物模型, 弱视模型制作, 评价

Abstract: Amblyopia is a common eye disease in children,which is a great problem for children’s life. It is important to establish an ideal animal model to study amblyopia. At present,the main method of making animal model of amblyopia are:suture of eyelid,cutting of rectus muscle,feeding in dark environment,and retinal detachment. This article reviewes the establishment of models,including animals, method, characteristics and discussed the frequently used models. This review will provide help for researchers in research design of animal models of amblyopia.

Key words: Amblyopia, animal model, preparation of amblyopia animal model, evaluation