关键词: 北京, 实验动物, 质量监测, 管理

Abstract: Ob jective To provide reference to production， management and detection of laboratory animal by analyzing of the recently 3 years'test result（2014—2016） on m icrobes and genetics of laboratory animals in Beijing.Method According to national and local standard and relevant law and regulation，Beijing Adm inistration Office of Laboratory Animal organized quality monitoring test for qualified laboratory animal manufacturers.According to the 3-year data from test reports，we can analyze the quality of different kinds of laboratory animal（including mice， rats， guineas， shrews，rabbits， dogs， monkeys and minipigs） in Beijing area.Result From 2014 to 2016， there were 120，133 and 130 batches of random testing annually， while 16，17，23 unqualified batches respectively.The main reason for disqualification is the immunity level dissatisfaction（49 batches in rabbits， dogs and minipigs）.There were also 3 batches genetic variation and 1 batch Pasteurella Pneumotropica positive in mice.1 batch Salmonella positive and 1 batch reovirusⅢ antibody positive were found in guineas，and 1 batch Salmonella positive was found in dogs.Conclusion Quality monitoring of laboratory animal is the important means for the quality management，and it can provide scientific data for the production and management of laboratory animals.

Key words: Beijing, laboratory animals, quality monitoring, management