实验动物科学 ›› 2018, Vol. 35 ›› Issue (04): 83-.

• 研究进展 • 上一篇    

哮喘动物模型建立的研究进展

  

  1. (1.天津中医药大学,天津 300193)(2.天津中医药大学第一附属医院呼吸科,天津 300193)
  • 出版日期:2018-08-28 发布日期:2020-08-28

esearch Progress on the Establishment of Animal Model of Asthma

  • Online:2018-08-28 Published:2020-08-28

摘要: 通过对近10年国内,外支气管哮喘动物建模方面实验研究的回顾与整理,总结哮喘动物模型建立及评价方面最新进展,发现过敏性哮喘模型仍是最经典与广泛复制的模型类型,而基于哮喘表型与异质性因素而提出的中性粒细胞哮喘、难治性哮喘模型的复制也取得一定进展。

关键词: 支气管哮喘, 动物模型, 卵清蛋白

Abstract: By reviewing and sorting out the experimental research on animal models of bronchial asthma in the past ten years, the latest progress in the establishment and evaluation of animal models of asthma is summarized. It is found that the allergic asthma model is still the most classic and widely replicated model type, and the neutrophils based on the phenotype and heterogeneity of asthma. The replication of cellular asthma and refractory asthma has also made some progress.

Key words: Bronchial asthma, animal model, Ovalbumin