实验动物科学 ›› 2018, Vol. 35 ›› Issue (03): 70-.

• 研究报告 • 上一篇    下一篇

全身麻醉对巴马小型猪空腹血糖测定的影响

  

  1. 中国人民解放军总医院医学实验动物中心,北京 100853
  • 出版日期:2018-06-28 发布日期:2020-08-28

Effect of General Anesthesia on Fasting Blood Glucose in Bama Miniature Pigs

  • Online:2018-06-28 Published:2020-08-28

摘要: 目的 探讨全身麻醉对高糖高脂饲料诱导的2型糖尿病巴马小型猪空腹血糖的影响。方法 巴马小型猪16头随机分为2组每组8头,对照组为正常饲料组,实验组为高糖高脂饲料诱导组。对16头巴马小型猪分别在全身麻醉前后测定空腹血糖,麻醉前后的血糖值进行组内、组间统计分析。结果 两组小型猪在麻醉前后空腹血糖值差异显著,高糖高脂饲料组麻醉后空腹血糖值升高与对照组差异极显著。结论 全身麻醉后巴马小型猪空腹血糖值明显升高,高糖高脂诱导的巴马小型猪2型糖尿病动物模型空腹血糖升高更为显著。

关键词: 巴马小型猪, 空腹血糖, 2型糖尿病, 麻醉

Abstract: Objective Investigating the effect of general anesthesia on fasting blood glucose in type 2 diabetic Bama miniature pigs induced by high glucose and high fat diet. Method Sixteen head of Bama miniature pigs were randomly divided into 2 groups, eight heads in each group, the control group was normal feed group, and the experimental group was feed by high glucose and high fat diet. Fasting blood glucose was measured before and after general anesthesia in sixteen Bama miniature pigs. The blood glucose values before and after anesthesia were statistically analyzed in the group and between groups. Result The difference of fasting blood glucose between the two groups was significant before and after the anesthesia, and the fasting blood glucose levels in the high fat and high fat diet group increased significantly compared with the control group. Conclusion After general anesthesia, the fasting blood glucose levels of Bama miniature pigs increased significantly, and the fasting blood glucose increased significantly in the type 2 diabetic induced by high glucose and high fat dietcompared with the control group.

Key words: Bama miniature pigs, fasting blood glucose, type 2 diabetic, anesthesia