关键词: 糖尿病近交系, 长爪沙鼠, 生物学特性

Abstract: Objective The basic data of genetic biochemical markers and biological characteristics of the breeding population of the inbred strain of Mongolian gerbil diabetes model. Method Using Beckman automatic biochemical analyzer (CX5) and Japan photoelectric automatic blood cell analyzer (MEK-7222 K) of 17 blood biochemical and 22 blood physiological indexes were determined; detection method of electrophoresis acetate fiber 26 biochemical marker; F20 rat, inbred animal production in accordance with the way of breeding, analysis of fetal the interval, number, weaning number statistics, growth curve. Result The result of the blood physiological and biochemical comparison between ALP, HDL-C and CRE index were significant differences (P<0.01); the difference of MCV, MCH, EOS, GLU, TG, LDH were significantly (P<0.05); a single genetic biochemical marker; birth weight is 2.68—3.38 g, the survival rate of weaning 68.31%, fetal long time. The quality of the 3—6 week old body weight increased rapidly. Conclusion The result of the study provide important reference materials for the identification of their lines and the application of biomedical applications.

Key words: Diabetic inbred line, Gerbil, biological characteristics