关键词: <, p>, 小鼠, 采血, 麻醉<, /p>

Abstract: Abstract: Objective To investigate the domestic situation of method of blood collection in mouse． Method The data was retrieved from Wan Fang database in the search term“mouse“and“blood”as defined by the 2012 to 2016 Journal Citation Ｒeports． Perform a statistical analysis on the articles which meet the criterion． Ｒesult Four hundred and forty-eight articles were retrieved，and 444 articles met the criterion． The most used three blood collection method are orbital sinus ( 33. 3% ) ，picking eyeball ( 22. 6% ) and tail vein ( 15. 4% ) ． Heart blood with anesthesia was 60 percent，and orbital sinus blood with anesthesia was 3. 2 percent． Conclusion The utilization rate of picking eyeball method is high． Given that it can cause great pain in mice，we suggest that replace this method with jaw venous plexus in pursuance or other method ． The rate of heart blood and orbital sinus with anaesthesia is not high． So it should be taken into account．

Key words: <p>mice, blood Collection, anesthesia</p>