关键词: <, p>, 内毒素, 脂多糖, 急性肺损伤, 急性呼吸窘迫综合征, 动物模型<, /p>

Abstract: Abstract: Acute lung injury ( ALI) and acute respiratory distress syndrome ( AＲDS) are common clinical syndrome with high mortality rate，and with no exactly effective treatments，which have not been researched thoroughly at present． Endotoxin / Lipopolysaccharide( LPS) has been reported as an important risk factor of ALI /AＲDS． The studies of ALI are mainly based on the animals，that its species and the responses to the inducer would always affect the trial． In this review，the characteristics of Endotoxin-induced animal model in ALI /AＲDS will be summarized．

Key words: <p>Endotoxin, Lipopolysaccharide ( LPS) , Acute lung injury( ALI), Acute respiratory distress syndrome ( AＲDS), Animal model</p>