关键词: <, p>, 肥胖, 强制运动, 自主运动<, /p>

Abstract: Abstract: Objective To study the influence on the weight of weaned mice by high fat food and forced sports，and the behavioral difference between dietary induced obesity ( DIO) and dietary induced obesity-resistant ( DIO-Ｒ) ．Method Fifty weaned mice were randomly divided into control group ( n = 60) and high-fat group ( n = 50) ，and fed normal and D12492 high fat diet respectively for 75 d． D12492 group was screened into obesity ( DIO) and obesity-resistant mice ( DIO-Ｒ) according to body weight，and then DIO ( n = 20) mice were divided into forced sports and control group ( n = 10) ． The mice in forced sports group were forced to have sports for an hour every day． The total cholesterol ( CHO) and triglyceride( TG) were measured by Hitachi automatic biochemical analyzer and activity were measured by roller recorder． Ｒesult There was significant difference for TC and TG between high fat food and normal food; After forced sports，the fat male mice reduce the fat more than female． Conclusion High fat food can induce the mice＇s obesity; forced sport can reduce the body weight in male animal，female mice with more voluntary wheel running were inclined to obesity resistant．

Key words: <p>Fat, forced sports, voluntary movement</p>