关键词: 盐敏感大鼠, 周龄, 遗传因素, 高盐饮食, 药理干预, 钾与钙的摄入

Abstract: Abstract: This paper describes the study of the origin and history of salt-sensitive rats，and analyzes the impact of changes in different age-related factors on blood pressure in salt-sensitive rats，including the impact of genetic factors in female offspring during pregnancy ( 21 days) of high salt intake，and comparing lactation ( 3 weeks after birth) ，pups or adolescence early ( 3 ～ 5 weeks) ，adolescence ( 6 ～ 8 weeks) and mature ( over 8 weeks) and other changes in blood pressure salt-sensitive rats differences after high salt intake，contrasting drug intervention ( thiazide diuretics，candesartan and eplerenone) for blood pressure levels of salt-sensitive rats in different age stages，and discussing the impact of potassium and calcium intake on blood pressure sensitive to the different stages of salt． By analyzing the factors affecting the level of salt sensitivity of blood pressure disease hypertensive rats， provide an effective basis for scientific experiments．

Key words: salt-sensitive rats, weeks, genetic factors, high-salt diet, pharmacological interventions, the intake of calcium and potassium