实验动物科学 ›› 2015, Vol. 32 ›› Issue (02): 48-52.

• 研究 论著 • 上一篇    下一篇

产后抑郁动物模型研究进展

  

  1. ( 1. 成都中医药大学,成都 610075) ( 2. 成都中医药大学附属医院,成都 610075)
  • 出版日期:2015-04-29 发布日期:2017-04-13
  • 基金资助:

    基金项目: 国家自然基金面上项目( No. 81373680)

Research Progress of Postpartum Depression of Animal Model

  • Online:2015-04-29 Published:2017-04-13

摘要: 摘要: 产后抑郁症是一种复杂情绪障碍疾病。由于在发病模式中所表现出的生理特殊性与病理复杂性,使得在本病动物模型研究方面与单纯抑郁症之间存在较大差异。产妇分娩后所处的特殊时期,其发病与激素水平、神经递质及某些肽类物质含量、相关受体功能等方面改变密切相关。在人体上研究产后抑郁症有很多局限性,有些研究内容需利用动物模型完成。本文结合近年来国内外相关文献,对目前常用的产后抑郁症动物模型进行简要综述,以供基础及临床研究参考。

关键词: 产后抑郁, 动物模型, 综述

Abstract: Abstract: Although Postpartum Depression belonging to one of the types of depression,as a complex mood disorders,it’s different from simple depression. During the special period of postpartum ,maternal hormone levels, content of neurotransmitters and neuropeptides,function of related receptor fluctuate dramatically and these fluctuations may contribute to the etiology of PPD. Because of the complexity of the physiological and pathological particularity makes big difference on the study of animal models between this disease and simple depression. We Combined with recent relevant literature and make a brief summary about currently used for postpartum depression in animal models in this article,so that it can provide a reference for researchs in expreimental study and clinical stady.

Key words: : postpartum depression, animal model, overview

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