关键词: 乌骨藤苷, 宫颈腺癌, 抑制

Abstract: Abstract: Objective To study the inhibiting effect of glaucescent fissistigma root crystals in the nude mice with cervical adenocarcinoma; Method Using cervical adenocarcinoma inoculated to the nude mice and growing the solid tumor，subcutaneous transplantation the 3th the solid tumor to establish nude mice model． Take glaucescent fissistigma root crystals ( I，II) from gastric for experimental，0. 5 mL /one，take water saline as control group ，one time per day，30 days in a row． Measuring the weight and tumor size 2 times in a week，after 30 days of treatment to put to death in mice，anatomize the mice and weighted tumor，calculate the tumor-inhibition rate． Evaluating the tumor-inhibit effection by glaucescent fissistigma root crystal Ⅰ and crystal Ⅱ in nude mice with cervical adenocarcinoma; Result Glaucescent fissistigma root crystalⅠ and crystalⅡ have affection to nude mice with cervical adenocarcinoma，the anti-tumor rate are 88. 95% and 66. 71% ，respectively． The tumor suppression of crystalⅠ have significant difference ( P＜0.01) ，crystalⅡ ( P＜0.05) ; Conclusion Glaucescent fissistigma root crystalⅠ and crystalⅡ can inhibit nude mice with cervical adenocarcinoma to growth．

Key words: glaucescent fissistigma root, cervical adenocarcinoma, inhibit