关键词:

凹土玉米芯, 垫料, KM 小鼠, 血生化

Abstract: Abstract: Objective To investigate the effects of bedding materials consisted of wood shavings，corn and the palygorskite corncob on the body weight，the blood biochemical parameters，pathological changes of KM mice． Method The 80 KM mice were divided into four groups randomly，20 in every group，with half male and half female，using the above-mentioned bedding materials and no bedding materials，respectively． The body weight were Weighed weekly，the blood biochemical parameters，including ALT，TP，ALP，LDH，T-SOD，ADH，were measured． Four weeks later，the pathological tissue organs were observed． Ｒesult Comparing with animals used the palygorskite corncob bedding，the weight of the male and the female KM mice in poplar bedding group was reduced from the third week，P ＜ 0. 05． Compared with the KM mice in the palygorskite corncob bedding group，LDH of KM mice in poplar bedding group was raised，significantly，P ＜ 0. 05; Compared with the KM mice in the palygorskite corncob bedding group，ADH of KM mice in poplar bedding group was reduced，significantly，P ＜ 0. 05; Compared with the KM mice in the palygorskite corncob bedding group，ALT of KM mice in poplar bedding and corn bedding groups were raised，significantly，P ＜ 0. 05; Significant pathological changes were not observed in the examined organs． Conclusion The palygorskite corncob bedding material has little effect on body weight，the blood biochemical parameters in KM mice，and the palygorskite corncob bedding material can be safely used in KM mice breeding．

Key words: palygorskite corncob, bedding, KM mice