实验动物科学 ›› 2014, Vol. 31 ›› Issue (03): 21-22.

• 研究 论著 • 上一篇    下一篇

利用灌注技术观察昆明小鼠 Willis 环的形态结构

  

  1. ( 长沙医学院基础医学院 长沙医学院科研实验中心,长沙 410219)
  • 出版日期:2014-06-29 发布日期:2016-12-05

Morphological Observation of Willis Ring Structure of the Kunming Mouse by Using a Perfusion Technique

  • Online:2014-06-29 Published:2016-12-05

摘要: 摘要: 目的 建立完整的昆明小鼠动脉环( Willis 环) 形态结构。方法 选用昆明小鼠利用灌注技术经左心室往脑 血管内灌注填充塑化剂约 2 mL,去骨取脑,观察 Willis 环结构。结果 该方法使复杂的小鼠脑血管及 Willis 环立体 清晰的显露出来。结论 我们采用灌注技术显示小鼠脑血管动脉环的形态结构,对小鼠脑血管的模型制作具有一 定的指导意义。

关键词: Willis 环, 脑缺血, 填充剂

Abstract: Abstract: To establish a fine morphological structure of Kunming mice arterial ring ( Willis ring) . Select Kunming mice by perfusion technology. Briefly infusing plasticizer about 2 ml from the left ventricle to cerebral vessel was performed,then skull bones were removed,and the structure of Willis ring was observed. This method made a fine cerebral vessel very clear and Willis ring clearly was revealed in the three-dimensional. We successfully adopted the perfusion technology to show the morphological structure of mice cerebral vessel which would play an important role for manufacturing the model of mice cerebral vessel.

Key words:

Willis ring, cerebral ischemia, plasticizer filler

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