实验动物科学 ›› 2013, Vol. 30 ›› Issue (05): 44-47.

• 研究 论著 • 上一篇    下一篇

高龄五指山小型猪近交系血液生化指标测定

  

  1. ( 中国农业科学院北京畜牧兽医研究所,北京100193)
  • 出版日期:2013-10-31 发布日期:2014-05-13
  • 基金资助:

    国家科技支撑( No. 2012BAI3904) ; 国家重点基础研究发展计划( 973 计划) ( No. 2011CB944202)

Blood Biochemical Tests of Senior Inbred Wuzhishan Miniature Pigs

  • Online:2013-10-31 Published:2014-05-13

摘要: 摘要: 目的了解猪龄和性别对五指山小型猪( WZSP) 近交系血液生化指标的影响。方法WZSP 近交系F17、F18 6 月龄青年猪34 头( 7♂,27♀) ,5—6 高龄猪21 头( 8♂,13♀) ,禁食12 h 后经由前腔静脉采血,用全自动生化分析 仪检测血液生化指标。结果青年猪和高龄猪有部分血液生化指标具有性别差异( P < 0. 05) ,其中青年猪有3 项 高龄猪有7 项; 青年猪和高龄猪有16 项血清生化指标具有差异( P < 0. 05) 。结论WZSP 近交系血液生化指标有 着明显的年龄差异,这对选用高龄猪作为人类老年化动物模型提供了基础参考数据。

关键词: 五指山小型猪, 生化指标, 高龄猪

Abstract: Abstract: Objective To analysis the blood biochemical parameters influenced by age and gender of inbreed Wuzhishan miniature pigs. Method 34 6-month-old pigs ( 7 ♂,27 ♀) ,as well as 21 pigs of 5—6 years old( 8 ♂,13♀) from F17,F18 offsprings of inbred WZSP were selected. After 12 hours of fasting,blood was collected via the superior vena cava and biochemical indexes were analyzed by full-Automatic biochemical analyzer. Result In all the blood biochemical indexes,3 of them showed gender differences ( P < 0. 05) between young pigs,while 7 of them showed gender differences ( P < 0. 05) among aged pigs. Meanwhile 16 of the blood biochemical indexes showed age differences ( P < 0. 05) . Conclusion The blood biochemical indexes of WZSP inbred lines display a significant age difference ( P < 0. 05) . This provides a basic reference data for choosing the aged miniature pigs as human aging animal models.  

Key words: Wuzhishan miniature pig, biochemical index, senior pig

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