关键词: 松花粉提取物, 高脂血症, 预防功效

Abstract: Abstract: Objective To evaluate preventive effect of pollen pini extract on experimental hyperlipoidemia in rats and offer evidence for application of pollen pini extract． Method Eighty four Wistar rats were randomly divided into normal control group，model group，0. 3，0. 15 and 0. 075 g /kg of pellen pini extract groups，simvastatin control group and solvent control group． The rats in normal control group were fed with normal feed． The rats in model group were fed with high fat diet and simultaneously received intragastric administration of distilled water． The rats in solvent control group were fed with high fat diet and simultaneously received intragastric administration grape seed oil． The animals in other groups were fed with high fat diet and simultaneously received intragastric administration the corresponding drug． 12 h after the last administration，the content of TC，TG，LDL-C and HDLC in serum were determined． Ｒesult In all doses of pollen pini extract groups，content of TC，TG，and LDL-C in serum were lower than that of model group ( P ＜ 0. 05—0. 01 ) ． In 0. 3 g /kg and 0. 15 g /kg of pollen pini extract groups，the atherogenic index were lower than that of the model group ( P ＜ 0. 05) ． Conclusion Pollen pini extracts have certain preventive function on experimental hyperlipidemia in rats．

Key words: Pellen pini extract, hyperlipoidemia, preventive effect