关键词: SX1近交系, 小鼠, 血液, 生化指标, 测定

Abstract: Objective To determine the main biochemical and blood indicators of inbred strains of mice SX1,and provide basic experimental data of this strain.Methods The 1,2,3,4-month-old mouse were chosen from the F29 and F30-generations,The following were recorded and analyzed :body weight,body length and tail length;the weight of 12 kinds of organs including heart,liver,spleen,lung;16 blood biochemical parameters including total protein,albumin,blood glucose,inosine;and 15 conventional indicators of blood including white blood cells, red blood cells,hemoglobin.Results The body weight,body length,tail length;heart,liver,spleen and other organs' s weight were growing in the growth of SX1 mice,while the thymus was narrowing.The organs's weight of male were larger than female,while adrenal gland of female was larger than male.There was no evident change in 14 blood biochemical parameters(including total protein,albumin) in the growth,but the indicators of total bilirubin and alkaline phosphatase were lower in the growth.No gender differences were exist in most indicators,but the indicator of alkaline phosphatase in female was higher than male.There was no obvious change in the 13 conventional indicators of the blood(including white blood cells,red blood cells) in the growth of the mice,but white blood cells and average thrombocytocrit were lower in the growth,and the white blood cells in male were higher than female.Conclusion Data and indices in this study confirmed the basical characteristics of this inbred strain of mice,and supplement the information of Inbred SX1 Mice.

Key words: SX1 inbred strain, Mice, Blood, Biochemical indicators, Determination