laboratory animal science
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Niu Tingxian; Shi Zhiyong
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牛廷献,史智勇
Abstract: The Purpose of this review is to discuss the ideal hepatic fibrosis animal model. In this review, rat, as laboratory animal, is suitable for the model; The model-making methods include Carbon tetracholride (CCl4), Bovine serum albumia (BSA), CCl4+BSA,Dimethylnitrosamine (DMN), Alcohol and Complex factors are discussed, as well as the hepatic pathological changes in each kind of model.
Key words: Rat. Hepatic Fibrosis Animal Model
摘要: 为探讨理想的肝纤维化动物模型,本文主要以大鼠为实验动物,综述了采用四氯化碳、血清白蛋白、四氯化碳+白蛋白、二甲基亚硝胺、乙醇及复合因素等造模方法,同时讨论了每一种模型的肝病理性变化。
关键词: 大鼠, 肝纤维化, 动物模型
Niu Tingxian; Shi Zhiyong. Study Advance in Hepatic Fibrosis Animal Model[J]. laboratory animal science.
牛廷献,史智勇. 肝纤维化动物模型的研究进展[J]. 实验动物科学.
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