laboratory animal science

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The Determination of Some Reference Values of Anti\|fatigue Test in Kunming Mice

GAO Shan,TONG Ying, WU Shao\|ping,XIONG Xiao\|yan   

  1. (Beijing Municipal Centre for Hygiene and Epidemic Control,Beijing\ 100013
  • Received:2001-03-25 Revised:2001-03-25 Online:2001-03-25 Published:2001-03-25

昆明种小鼠抗疲劳试验中若干参考值测定

高珊,童英,吴少平,熊晓燕   

  1. 北京市疾病预防控制中心毒理科!北京100013,北京市疾病预防控制中心毒理科!北京100013,北京市疾病预防控制中心毒理科!北京100013,北京市疾病预防控制中心毒理科!北京100013

Abstract: Four indices of anti\|fatigue test were studied in this paper,in order to discern dynamic changes and determine reference values of each index.the results show that reference value of swimming time is 196~1420 seconds in mice burdened with weight of 5% body weight (density is 48cm 2 each mouse,water temperature is 25℃);reference value of blood lactate is 1.77~6.56mmol/L in a state of quiet,and 3.55~9.29mmol/L after brief acute movement in mice;serum urea nitrogen is 7.86~13.14mmol/L in base condition,and 6.97~24.90mmol/L after long duration movement;liver hepatin is 1452.8~5279.4mg/100g liver weight in base state,and 39.9~3163.3mg/100g liver weight after long duration acute movement.

Key words: Mouse, Burdened swimming, Blood lactate, Serum urea nitrogen, Liver hepatin, Reference value

摘要: :本文就抗疲劳功能试验中的四项指标进行研究分析 ,旨在了解各项指标的动态变化 ,确定其参考值。结果显示 :小鼠负重 (5 %体重 )游泳时间参考值为 196~ 142 0s(密度为 48cm2 只 ,2 5℃水温 ) ;小鼠基础血乳酸参考值为1 77~ 6 5 6mmol L ;短时剧烈运动血乳酸参考值为 3 5 5~ 9 2 9mmol L ;小鼠基础血清尿素氮参考值为 7 86~ 13 14mmol L ;长时运动后血清尿素氮参考值为 6 97~ 2 4 90mmol L ;小鼠基础肝糖原参考值为 145 2 8~ 5 2 79 4mg 10 0g肝组织 ,长时大强度运动后肝糖原参考值为 39 9~ 316 3 3mg 10 0g肝组织

关键词: 小鼠, 负重游泳, 血乳酸, 血清尿素氮, 肝糖原, 参考值