The Weight of Main Organs and Organ Coefficient in 10 kinds of Common SPF Rats and Mice

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The Weight of Main Organs and Organ Coefficient in 10 kinds of Common SPF Rats and Mice

LU Sheng-ming~1,HU Jian-wu~1,CHE Lu-ping~1,WANG Xiao-lu~1,SUN Yan-song~2,SHI Yan-sheng~2,HE Zheng-ming~3,WANG Hong~3,LIU Shuang-huan~3,RONG Rui-zhang~4

(1.Beijing Laboratory Animal Research Centre,Beijing 100012,China)(2.Laboratory Animal Center,Academy of Military Medicine Science,Beijing 100071,China)(3.National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050,China)(4.Beijing Administration Office of Laboratory Animal,Beijing 100089,China

Received:2007-06-28 Revised:2007-06-28 Online:2007-06-28 Published:2007-06-28

10种常用SPF级实验大、小鼠体重及主要脏器的测定

卢胜明;胡建武;车路平;王晓鹭;孙岩松;时彦胜;贺争鸣;王洪;刘双环;荣瑞章;

北京实验动物研究中心,北京实验动物研究中心,北京实验动物研究中心,北京实验动物研究中心,军事医学科学院实验动物中心,军事医学科学院实验动物中心,中国药品生物制品检定所,中国药品生物制品检定所,中国药品生物制品检定所,北京市实验动物管理办公室北京100012,北京100012,北京100012,北京100012,北京100071,北京100071,北京100050,北京100050,北京100050,北京100089

Abstract

Abstract: Objective To measure the indexes of normal organ weight and organ coefficient of 10 kinds of usual SPF grade rats and mice.Methods Dissects 10 kinds of strains laboratory animal,determined the normal weight and organ coefficient of the relative weight,measured intestinal tract length with the ruler,which has altogether carried on the determination to 9 kinds of organs coefficient.Results There are showed very significant difference in age-related,sex-related,and strain-related,so on difference existed in the same strains because of of different sexes.

Key words: SPF grade, Rat, Mouse, Organ coefficient

摘要： 目的测定10种常用SPF级大、小鼠体重、脏器及肠道等正常参考值。方法解剖10种品系实验动物,称量各组织脏器的相对重量,用尺测量肠道长度,共对9种脏器指标进行了测定。结果不同品系动物的各种脏器指标有明显差别,即使是同种品系,不同性别间也存在差异。

关键词: SPF级, 大、小鼠, 脏器

LU Sheng-ming~1,HU Jian-wu~1,CHE Lu-ping~1,WANG Xiao-lu~1,SUN Yan-song~2,SHI Yan-sheng~2,HE Zheng-ming~3,WANG Hong~3,LIU Shuang-huan~3,RONG Rui-zhang~4. The Weight of Main Organs and Organ Coefficient in 10 kinds of Common SPF Rats and Mice[J]. laboratory animal science.

卢胜明;胡建武;车路平;王晓鹭;孙岩松;时彦胜;贺争鸣;王洪;刘双环;荣瑞章;. 10种常用SPF级实验大、小鼠体重及主要脏器的测定[J]. 实验动物科学.

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