A New Method of The Indwelling Catheter in The Rat External Jugular Vein

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A New Method of The Indwelling Catheter in The Rat External Jugular Vein

WANG Jing-jing,JIAO Kun,LI Bing,YIN Zhao-xue,MENG Xia,QIAO Xin,XIAO Ying-qiu,LU Jing

(Capital Medical University,Beijing 100069,China

Received:2008-04-28 Revised:2008-04-28 Online:2008-04-28 Published:2008-04-28

介绍一种新的大鼠颈外静脉插管方法

王晶晶;焦昆;李兵;殷召雪;孟霞;乔欣;肖迎秋;卢静;

首都医科大学,首都医科大学,首都医科大学,首都医科大学,首都医科大学,首都医科大学,首都医科大学,首都医科大学北京100069,北京100069,北京100069,北京100069,北京100069,北京100069,北京100069,北京100069

Abstract

Abstract: To introduce a method of placing a catheter into the rat external jugular vein for collecting blood samples and administration of therapeutic drugs in the studies on pharmaceutical toxicokinetics.It is convenient to infuse drugs or to draw blood samples repeatedly for avoiding multi-injury to animals.

Key words: Rats, External jugular vein, Intravenous intubation, Drug administration, Blood sampling

摘要： 为解决药物毒代动力学实验中对大鼠静脉反复给药、取血的操作问题,采用颈外静脉插管的方法在动物体内埋入导管,通过此管来完成给药、取血的工作。此法简便、易行且对动物损伤小。

关键词: 大鼠, 颈外静脉, 静脉插管, 给药, 采血

WANG Jing-jing,JIAO Kun,LI Bing,YIN Zhao-xue,MENG Xia,QIAO Xin,XIAO Ying-qiu,LU Jing. A New Method of The Indwelling Catheter in The Rat External Jugular Vein[J]. laboratory animal science.

王晶晶;焦昆;李兵;殷召雪;孟霞;乔欣;肖迎秋;卢静;. 介绍一种新的大鼠颈外静脉插管方法[J]. 实验动物科学.

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A New Method of The Indwelling Catheter in The Rat External Jugular Vein

介绍一种新的大鼠颈外静脉插管方法

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