Abstract: Objective To investigate antifatigue effect of Huili Capsule(回力胶囊 Capsule for Restoring Physical Strength) by swimming test in the mice.Methods Huili Capsule was orally administered to the mice at high,middle and low dose for 30 successive days.Loaded swimming was carried out in the mice.Loaded swimming duration was recorded,and glycogen level in liver,urea nitrogen level in serum,and blood lactic acid level were determined.Results As compared with the control group,loaded swimming duration was prolonged in the groups of high and middle dose.Blood lactic acid level after loaded swimming in the groups of high and middle dose was lower than that in the control group,urea nitrogen level in serum in the group of high dose was lower than that in the control group,and glycogen level in liver in group of high dose was higher than that in the control group.Conclusion Huili Capsule can exert antifatigue effect.

Key words: Huili Capsule(Capsule for Restoring Physical Strength), Antifatigue effect, Swimming test in the mice

摘要： 目的通过小鼠游泳试验研究回力胶囊缓解疲劳的作用。方法小鼠负重游泳试验,血清尿素氮、肝糖原、血乳酸测定。结果在连续给予小鼠回力胶囊30 d后,与阴性对照组比较,高、中剂量组小鼠的游泳时间显著延长(P<0.01)、(P<0.05);游泳后高、中剂量组的血乳酸增长显著降低(P<0.05);高剂量组小鼠血清尿素氮含量显著降低(P<0.05);高剂量组小鼠肝糖原含量显著增加(P<0.01)。结论回力胶囊具有缓解体力疲劳的作用。

关键词: 回力胶囊, 缓解体力疲劳作用, 小鼠游泳试验